The Chicago White Sox defeated the San Francisco Giants 9-4 in an interleague matchup at Oracle Park on Friday, May 22, 2026. The big takeaway was a dramatic 9-run fourth inning in which the White Sox did not hit a home run and managed only five hits across the game. Munetaka Murakami delivered the standout moment with a bases-clearing three-run double during the pivotal frame, complementing an earlier two-run double from Andrew Benintendi.
Starting pitcher Davis Martin earned the win, moving to 7-1 after 5.2 innings and seven strikeouts. Trevor McDonald was charged with the loss after allowing seven runs in 3.2 innings. With this result, the White Sox added another win to their early-season campaign, while the Giants faced a setback on the mound and at the plate that limited their offensive production in the early innings.