Week 4 of college football features a series of notable matchups, including the Michigan-Iowa game and the USC-Oregon contest. This week is noted for having the highest number of ranked games since 2023. Predictions and betting lines are available for the top 20 matchups. Live updates, schedules, and scores are tracked on NCAA.com. Donald Trump attended a game with a plan to protect communications. Live broadcasts are available on SiriusXM and local stations.